The Science Behind Alkalinity

Why Sell a Product When You Can Sell a Concept

Promoting ways to prolong longevity since the early 1900's.

The ALKALINE diet provides your pet with the proper pH Balance to oxygenate the blood, which reduces anaerobic activity and cellular degeneration ( aging ).

Historical Studies

Novel insights into the pathogenesis of uric acid nephrolithiasis by Naim M. Maalouf

Summary: The recognition of metabolic factors that influence urinary pH, and uric acid metabolism and excretion, will provide novel insights into the pathogenesis of uric acid stones, and open the way for new therapeutic strategies.

Experimental Determination of Net Protein Charge and Atot and Ka of Novolatile Buffers in Canine Plasma by Peter D. Constable and Henry R Stämpfli

Summary: application of the experimentally determined values for Atot Ka, and net protein charge of canine plasma should improve understanding of the mechanism for complex acid-base disturbances in critically ill dogs.

Experientia by P. Vaupel

Summary: pH declined during growth with intracellular acidosis being evident in tumors >350mm3. Whereas lactic acid formation greatly contributed to this decline in small and medium-sized tumors, adenosine triphosphate (ATP) hydrolysis and slowing down of the activities of pumps involved in cellular pH regulation seem to be major factors responsible for intracellular acidification in bulky tumors relatively constant. This coincided with intracellular alkalosis or neutrality and stable adenylate ratios. On average, median pO2 values <10 mmHg coincided with intracellular acidosis, ATP depletion, a drop in energy charge and rising Pi levels.

The Alkaline Diet: Is There Evidence That an Alkaline pH Diet Benefits Health? by Gerry K. Schwalfenberg

Summary: Alkaline diets result in a more alkaline urine pH and may result in reduced calcium in the urine. Alkaline diets may benefit bone health, reduce muscle wasting, as well as mitigate other chronic diseases such as hypertension and strokes. An alkaline diet may improve many outcomes from cardiovascular health to memory and cognition. An increase in intracellular magnesium, which is required for the function of many enzyme systems. Alkalinity may result in added benefit for some chemotherapeutic agents that require a higher pH.

Diet, evolution and aging-- the pathophysiologic effects of the post-agricultural inversion of the potassium-to-sodium and base-to-chloride ratios by Lynda A. Frassetto

Summary: We argue that any level of acidosis may be unacceptable from an evolutionarily perspective, and indeed, that a low-grade metabolic alkalosis may be the optimal acid-base state.

Regulation of bone cell function by acid-base balance by Tim Arnett

Summary: Results suggest that even subtle chronic acidosis could be sufficient to cause appreciable bone loss over time.

Diet-induced acidosis: is it real and clinically relevant? by Lynda A. Frassetto

Summary: Research makes a compelling case that diet-induced acidosis is a real phenomenon, has significant clinical relevance, may largely be prevented through dietary changes, and should be recognized and treated.

Steward and beyond: New Models of acid-base balance by Howard E. Corey

Summary: Although the pH remains normal initially, such patients easily develop acidemia when stressed because of the steepness of the pH vs. SID plot at low [SID+].